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Case Report
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Primary malignant lymphoma of testis in a young immune competent adult: A case report | ||||||
Vandana Rana1, Devika Gupta1, Rajat Jagani1, Giriraj Singh2 | ||||||
1Associate Professor, Armed Forces Medical College, Department of Pathology and Laboratory Science, Command Hospital, Pune, India.
2Associate Professor, Armed Forces Medical College, Department of Radio diagnosis and Imaging, Command Hospital, Pune, India. | ||||||
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Rana V, Gupta D, Jagani R, Singh G. Primary malignant lymphoma of testis in a young immune competent adult: A case report. Edorium J Pathol 2014;1:1–5. |
Abstract
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Introduction:
Primary testicular lymphoma (PTL) is a disease of elderly and is very rarely seen in young adults. In the era of human immunodeficiency virus (HIV) pandemic, changing age spectrum has been reported but it is an uncommon malignancy in immune competent young adult. Chances of misdiagnosis or delayed diagnosis are there due to same age group of presentation as that of germ cell tumors.
Case Report: A 35-year-old immune competent male presented with left testicular swelling for five months duration, he was being treated as a case of epididymo-orchitis. On fine-needle aspiration cytology impression of seminoma was favored but it turned out to be non-Hodgkin's lymphoma (NHL) of testis on histopathology following orchidectomy. There was no evidence of generalized lymphadenopathy or involvement of any other organ. On immunohistochemistry (IHC) studies diagnosis of diffuse large B cell lymphoma (DLBCL), non germinal cell type was made. Conclusion: Testicular lymphomas are rare and aggressive tumors and timely diagnosis in early stage helps the prognosis. Even though our patient was immune competent, in the era of human immunodeficiency virus (HIV) pandemic with changing age spectrum it is important to consider lymphomas in differential diagnosis of testicular tumors even in young patients. | |
Keywords:
Diffuse large B cell lymphoma (DLBCL), Human immunodeficiency virus (HIV), Primary testicular lymphoma (PTL), Immunohistochemistry (IHC), Lymphoma, Seminoma, non-Hodgkin's lymphoma (NHL), Testis
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Author Contributions
Vandana Rana – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Devika Gupta – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Rajat Jagani – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published Giriraj Singh – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published |
Guarantor of submission
The corresponding author is the guarantor of submission. |
Source of support
None |
Conflict of interest
Authors declare no conflict of interest. |
Copyright
© 2014 Vandana Rana et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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About The Authors
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